Projects
OptiMISing induction of labour care: a pilot randomised controlled trial of outpatient low-dose oral, misoprostol versus balloon catheter dilatation
RBWH Foundation Grants Round 6
Share this project
Project description
Researchers at Royal Brisbane and Women's Hospital (RBWH) are exploring whether inducing labour at home might be an option for some women experiencing a low-risk pregnancy.
Building on promising earlier research, the team is testing a low-dose oral medication that could enable women to begin labour in the comfort of their own home, with structured support and clear pathways to hospital when needed.
The study will examine whether this approach is safe for mothers and babies while giving women greater choice, comfort and control over their birth experience.
Why this work is needed
Labour induction has become increasingly common, but for many women the experience can be lengthy, stressful and highly medicalised.
Current induction methods often require women to spend many hours - and sometimes days - in hospital before active labour begins. Many describe feeling anxious, uncomfortable and disconnected from their normal routines during this waiting period, with little opportunity to rest or remain in familiar surroundings.
For women with low-risk pregnancies, there may be another option.
This project will investigate whether eligible women can safely begin labour induction at home using a low-dose oral medication, moving to hospital only when labour progresses or clinical care is needed. Researchers will carefully compare the safety of this approach with standard hospital-based induction, while also measuring women's experiences, comfort and satisfaction.
Expected outcomes
The long-term goal is to provide evidence for a more personalised approach to labour induction that gives women greater choice without compromising the safety of mothers or babies. If successful, this model-of-care could also reduce unnecessary hospital stays and help maternity services use beds and staff more efficiently, benefiting both families and the healthcare system.

