Projects

A multi-centre prospective cohort study of VTE prophylaxis prescribing practices in the Australian trauma ICU population

RBWH Foundation Grants Round 5
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Project description

Following traumatic injury there is a high likelihood the patient may have substantial blood clots, such as deep vein thrombosis and pulmonary embolisms.

This study will collect data from intensive care units (ICU) across Australia, about which blood thinners are routinely used, along with their dose and timing.

Why this work is needed

ICU patients with severe traumatic injuries are at high risk of forming blood clots in their limbs and lungs. These clots, known as venous thromboembolisms (VTE) can lead to serious complications including death.

Approximately 12% of trauma patients admitted to the RBWH ICU will develop a blood clot during their hospital admission. These clots contribute to poor outcomes and potentially death. 

To reduce the risk, medications to thin the blood are given to trauma patients. However, the best type of blood thinner, dose and timing of administration is not well understood.

Expected outcomes

This study will provide comprehensive data about incidence of VTEs and the routine use of medications to prevent or treat them. This information will be used to design a large clinical trial.

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Lead Researcher

Dr Elissa Milford

Staff Specialist, Intensive Care Services, RBWH